Royal Free London NHS Foundation Trust

Royal Free Hospital Manufacturing Pharmacy

The project:
The Royal Free London NHS Foundation Trust has one of the larger hospital pharmaceutical production units in the country. They hold a manufacturer’s ‘specials’ licence, an investigational medicinal products (IMP) licence and a wholesale dealer’s licence and are able to make and distribute a wide range of products.

Quality through design:
Refurbishment was required for the current manufacturing pharmacy to create state-of-the-art facilities for the hospital and included the remodelling of the existing manufacturing pharmacy Aseptic and Civas suites to provide a facility which achieves MHRA compliance.

Works include the strip out and demolition of the existing facilities, new walls, ceiling and floor finishes together with specialist pass through hatches and laboratory furniture. Services need to meet specific air pressure regimes to ensure that parts of the facility are maintained under positive pressure to avoid cross contamination of product.

Collaborative working:
The refurbishment comprises of three separate phases running concurrently: Non-sterile production, civas and the quality control lab.

Initially, the quality control lab and quarantine room had to be re-sited as part of enabling works.

In order to ensure minimal disruption, the Manufacturing Pharmacy continued to operate the drug production area (Cytos Lab), whilst an extensive refurbishment of the facilities was undertaken in the adjacent area. Crucially all M&E services to the Cytos area remained fully operational, to ensure that drop in air pressure did not occur which would result in a loss of up to 30 days in drug production.

Close liaison with the client was essential to avoid any potential issues and it was crucial to communicate constantly with senior members of the department with regards to the shutdown of any services.

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Project Name: Royal Free Hospital Manufacturing Pharmacy

Location: Royal Free Hospital, Pond Street, London NW3 2QG

Value: £1.7m

Principal Consultants: AHP Architects, AECOM

Project Duration: 26 weeks

Initially, we were required to undertake enabling works prior to the installation of new services... Close liaison with the client was essential to avoid any potential issues.